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Auto-segmentation and time-dependent systematic analysis of mesoscale cellular structure in β-cells during insulin secretion.
The mesoscale description of the subcellular organization informs about cellular mechanisms in disease state. However, applications of soft X-ray tomography (SXT), an important approach for characterizing organelle organization, are limited by labor-intensive manual segmentation. Here we report a pi...
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| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2022-01-01
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| Schriftenreihe: | PLoS ONE |
| Online Zugang: | https://doi.org/10.1371/journal.pone.0265567 |
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