Noninvasive molecular diagnosis of craniopharyngioma with MRI-based radiomics approach

Abstract Background Frequent somatic mutations of BRAF and CTNNB1 were identified in both histological subtypes of craniopharyngioma (adamantinomatous and papillary) which shed light on target therapy to cure this oncogenic disease. The aim of this study was to investigate the noninvasive MRI-based...

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Main Authors: Xi Chen, Yusheng Tong, Zhifeng Shi, Hong Chen, Zhong Yang, Yuanyuan Wang, Liang Chen, Jinhua Yu
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2019-01-01
Series:BMC Neurology
Assuntos:
Craniopharyngioma
Molecular diagnosis
Radiomics approach
Non-invasiveness
Machine learning
Acceso en liña:http://link.springer.com/article/10.1186/s12883-018-1216-z
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