Noninvasive molecular diagnosis of craniopharyngioma with MRI-based radiomics approach

Abstract Background Frequent somatic mutations of BRAF and CTNNB1 were identified in both histological subtypes of craniopharyngioma (adamantinomatous and papillary) which shed light on target therapy to cure this oncogenic disease. The aim of this study was to investigate the noninvasive MRI-based...

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Main Authors: Xi Chen, Yusheng Tong, Zhifeng Shi, Hong Chen, Zhong Yang, Yuanyuan Wang, Liang Chen, Jinhua Yu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-01-01
Serier:BMC Neurology
Fag:
Craniopharyngioma
Molecular diagnosis
Radiomics approach
Non-invasiveness
Machine learning
Online adgang:http://link.springer.com/article/10.1186/s12883-018-1216-z
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