Plasma Membrane Localization of CD36 Requires Vimentin Phosphorylation; A Mechanism by Which Macrophage Vimentin Promotes Atherosclerosis

Vimentin is a type III intermediate filament protein expressed in cells of mesenchymal origin. Vimentin has been thought to function mainly as a structural protein and roles of vimentin in other cellular processes have not been extensively studied. Our current study aims to reveal functions of vimen...

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Hauptverfasser: Seo Yeon Kim, Se-Jin Jeong, Ji-Hae Park, Wonkyoung Cho, Young-Ho Ahn, Youn-Hee Choi, Goo Taeg Oh, Roy L. Silverstein, Young Mi Park
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-05-01
Schriftenreihe:Frontiers in Cardiovascular Medicine
Schlagworte:
vimentin
atherosclerosis
CD36
macrophage
intracellular trafficking
Online Zugang:https://www.frontiersin.org/articles/10.3389/fcvm.2022.792717/full
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