Enhanced anti-proliferative and pro-apoptotic effects of metformin encapsulated PLGA-PEG nanoparticles on SKOV3 human ovarian carcinoma cells

Metformin (MET) has received considerable attention in recent years for its anticancer potential activities. However, short half-life and weak bioavailability of MET limited its use as a chemotherapeutic agent. The present study is intended to evaluate the efficiency of PLGA-PEG as a nano-carrier fo...

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Detaylı Bibliyografya
Asıl Yazarlar: Leila Faramarzi, Mehdi Dadashpour, Hadi Sadeghzadeh, Majid Mahdavi, Nosratollah Zarghami
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2019-12-01
Seri Bilgileri:Artificial Cells, Nanomedicine, and Biotechnology
Konular:
Metformin
polymeric nanoparticles
apoptotic effect
ovarian cancer
Online Erişim:https://www.tandfonline.com/doi/10.1080/21691401.2019.1573737
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