Hyperoside Protected Against Oxidative Stress-Induced Liver Injury via the PHLPP2-AKT-GSK-3β Signaling Pathway In Vivo and In Vitro

Hyperoside, isolated from Drosera rotundifolia L., seeds of Cuscuta chinensis Lam., or Hypericum perforatum L., originally showed to possess an antifungal and antibacterial activity, while recently showed the protective effects against oxidative stress-induced liver injury. This study investigated s...

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Главные авторы: Haiyan Xing, Ruoqiu Fu, Caiyi Cheng, Yongqing Cai, Xianfeng Wang, Dongmei Deng, Xiaoyuan Gong, Jianhong Chen
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020-07-01
Серии:Frontiers in Pharmacology
Предметы:
hyperoside
liver injury
oxidative stress
pleckstrin homology domain leucine-rich repeat protein phosphatase 2
nuclear factor erythroid-2-related factor 2
glycogen synthase kinase 3β
Online-ссылка:https://www.frontiersin.org/article/10.3389/fphar.2020.01065/full
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