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Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.

BACKGROUND:Adenosine is generated in response to cellular stress and damage and is elevated in the lungs of patients with chronic lung disease. Adenosine signaling through its cell surface receptors serves as an amplifier of chronic lung disorders, suggesting adenosine-based therapeutics may be bene...

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Библиографические подробности
Главные авторы: Yang Zhou, Jayasimha N Murthy, Dewan Zeng, Luiz Belardinelli, Michael R Blackburn
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2010-02-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC2821921?pdf=render
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