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HMGB1: The Central Cytokine for all Lymphoid Cells

High mobility group box 1 (HMGB1) is a leaderless cytokine, like the IL-1 and FGF family members, that has primary roles within the nucleus and the cytosol. Within the nucleus, it serves as another guardian of the genome, protecting it from oxidant injury and promoting access to transcriptional comp...

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Détails bibliographiques
Auteurs principaux: Guanqiao eLi, Xiaoyan eLiang, Michael Thomas Lotze
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2013-03-01
Collection:Frontiers in Immunology
Sujets:
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Accès en ligne:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00068/full
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