Improving l-serine formation by Escherichia coli by reduced uptake of produced l-serine

Abstract Background Microbial de novo production of l-serine, which is widely used in a range of cosmetic and pharmaceutical products, has attracted increasing attention due to its environmentally friendly characteristics. Previous pioneering work mainly focused on l-serine anabolism; however, in th...

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Hauptverfasser: Chenyang Wang, Junjun Wu, Binchao Shi, Jiping Shi, Zhijun Zhao
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-03-01
Schriftenreihe:Microbial Cell Factories
Schlagworte:
l-serine
Uptake system
Gene knockout
Fermentation of l-serine
Online Zugang:http://link.springer.com/article/10.1186/s12934-020-01323-2
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