Catalpol Suppresses Proliferation and Facilitates Apoptosis of OVCAR-3 Ovarian Cancer Cells through Upregulating MicroRNA-200 and Downregulating MMP-2 Expression

Catalpol is expected to possess diverse pharmacological actions including anti-cancer, anti-inflammatory and hypoglycemic properties. Matrix metalloproteinase-2 (MMP-2) is closely related to the pathogenesis of ovarian cancer. In addition, microRNA-200 (miR-200) can modulate phenotype, proliferation...

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Bibliografski detalji
Glavni autori: Na Gao, Jian-Xin Tian, Yu-Hong Shang, Dan-Yi Zhao, Tao Wu
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2014-10-01
Serija:International Journal of Molecular Sciences
Teme:
catalpol
ovarian cancer
OVCAR-3 cell
MicroRNA-200
matrix metalloproteinase-2
Online pristup:http://www.mdpi.com/1422-0067/15/11/19394
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