Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/Non-parametric Tools for Improved Diagnostic Biomarker Identification.

A temporal study of gene expression in peripheral blood leukocytes (PBLs) from a Mycobacterium tuberculosis primary, pulmonary challenge model Macaca fascicularis has been conducted. PBL samples were taken prior to challenge and at one, two, four and six weeks post-challenge and labelled, purified R...

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Hauptverfasser: Sajid Javed, Leanne Marsay, Alice Wareham, Kuiama S Lewandowski, Ann Williams, Michael J Dennis, Sally Sharpe, Richard Vipond, Nigel Silman, Graham Ball, Karen E Kempsell
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2016-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC4882019?pdf=render
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