Chloroquine Inhibits Stemness of Esophageal Squamous Cell Carcinoma Cells Through Targeting CXCR4-STAT3 Pathway

Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent cancers worldwide. Recent studies have shown that cancer stem cells (CSCs) are present in ESCC, are thought to lead to aggressive tumor behavior and the prognosis. The CXC chemokine receptor 4 (CXCR4), is regarded as a putative C...

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Main Authors: Dongli Yue, Daiqun Zhang, Xiaojuan Shi, Shasha Liu, Anqi Li, Dong Wang, Guohui Qin, Yu Ping, Yamin Qiao, Xinfeng Chen, Feng Wang, Renyin Chen, Song Zhao, Lidong Wang, Yi Zhang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Oncology
Assuntos:
esophageal squamous cell carcinoma (ESCC)
cancer stem cells (CSCs)
CXCR4
chloroquine (CQ)
STAT3
Acceso en liña:https://www.frontiersin.org/article/10.3389/fonc.2020.00311/full
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