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Whole-genome sequencing and assembly with high-throughput, short-read technologies.

While recently developed short-read sequencing technologies may dramatically reduce the sequencing cost and eventually achieve the $1000 goal for re-sequencing, their limitations prevent the de novo sequencing of eukaryotic genomes with the standard shotgun sequencing protocol. We present SHRAP (SHo...

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Main Authors: Andreas Sundquist, Mostafa Ronaghi, Haixu Tang, Pavel Pevzner, Serafim Batzoglou
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2007-05-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC1871613?pdf=render
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