Activation of PKA/CREB Signaling is Involved in BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells

Background/Aims: BMP9 is highly capable of promoting osteogenic differentiation of mesenchymal stem cells (MSCs) although the molecular mechanism involved is largely unknown. Here, we explored the detail role of PKA/CREB signaling in BMP9-induced osteogenic differentiation. Methods: Activation statu...

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Hlavní autoři: Hongyu Zhang, Li Li, Qian Dong, Yufeng Wang, Qiaoling Feng, Xinying Ou, Pengfei Zhou, Tongchuan He, Jinyong Luo
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Physiol Biochem Press GmbH & Co KG 2015-09-01
Edice:Cellular Physiology and Biochemistry
Témata:
BMP9
PKA
CREB
Mesenchymal stem cells
Osteogenesis
Osteogenic differentiation
H89
On-line přístup:http://www.karger.com/Article/FullText/430376
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