Biguanides enhance antifungal activity against Candida glabrata

Candida spp. are the fourth leading cause of nosocomial blood stream infections in North America. Candida glabrata is the second most frequently isolated species, and rapid development of antifungal resistance has made treatment a challenge. In this study, we investigate the therapeutic potential of...

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Bibliographische Detailangaben
Hauptverfasser: Shuying Xu, Marianela Feliu, Allison K. Lord, Daniel P. Lukason, Paige E. Negoro, Nida S. Khan, Zeina Dagher, Michael B. Feldman, Jennifer L. Reedy, Samantha N. Steiger, Jenny M. Tam, Alexander A. Soukas, David B. Sykes, Michael K. Mansour
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2018-12-01
Schriftenreihe:Virulence
Schlagworte:
Candida
Candida glabrata
biguanide
drug resistance
metformin
minimum inhibitory concentration (MIC)
Online Zugang:http://dx.doi.org/10.1080/21505594.2018.1475798
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