Biguanides enhance antifungal activity against Candida glabrata

Candida spp. are the fourth leading cause of nosocomial blood stream infections in North America. Candida glabrata is the second most frequently isolated species, and rapid development of antifungal resistance has made treatment a challenge. In this study, we investigate the therapeutic potential of...

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Bibliographic Details
Main Authors: Shuying Xu, Marianela Feliu, Allison K. Lord, Daniel P. Lukason, Paige E. Negoro, Nida S. Khan, Zeina Dagher, Michael B. Feldman, Jennifer L. Reedy, Samantha N. Steiger, Jenny M. Tam, Alexander A. Soukas, David B. Sykes, Michael K. Mansour
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
Candida
Candida glabrata
biguanide
drug resistance
metformin
minimum inhibitory concentration (MIC)
Online Access:http://dx.doi.org/10.1080/21505594.2018.1475798
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