The Antitumor Effect of Heparin is not Mediated by Direct NK Cell Activation

Natural killer (NK) cells are innate lymphocytes responsible for the elimination of infected or transformed cells. The activation or inhibition of NK cells is determined by the balance of target cell ligand recognition by stimulatory and inhibitory receptors on their surface. Previous reports have s...

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Main Authors: Gustavo R. Rossi, Jenifer P. Gonçalves, Timothy McCulloch, Rebecca B. Delconte, Robert J. Hennessy, Nicholas D. Huntington, Edvaldo S. Trindade, Fernando Souza-Fonseca-Guimaraes
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-08-01
Serier:Journal of Clinical Medicine
Fag:
NK cells
cancer
heparin
antitumor responses
Online adgang:https://www.mdpi.com/2077-0383/9/8/2666
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