Statistical optimisation of process variables and large-scale production of Metarhizium rileyi (Ascomycetes: Hypocreales) microsclerotia in submerged fermentation

Microsclerotia (MS) formation was successfully induced in Metarhizium rileyi (Ascomycetes: Hypocreales) in liquid culture. To optimise the process variables of liquid fermentation, we first used a two-level fraction design to confirm the variables, including inoculum density, initial pH, shaker spee...

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Main Authors: Zhangyong Song, Yunlong Lin, Fang Du, Youping Yin, Zhongkang Wang
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis Group 2017-01-01
Series:Mycology
Assuntos:
Metarhizium rileyi
microsclerotia
submerged fermentation
central composite design
response surface methodology
aeration and agitation rate
Acceso en liña:http://dx.doi.org/10.1080/21501203.2017.1279688
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