Statistical optimisation of process variables and large-scale production of Metarhizium rileyi (Ascomycetes: Hypocreales) microsclerotia in submerged fermentation

Microsclerotia (MS) formation was successfully induced in Metarhizium rileyi (Ascomycetes: Hypocreales) in liquid culture. To optimise the process variables of liquid fermentation, we first used a two-level fraction design to confirm the variables, including inoculum density, initial pH, shaker spee...

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Auteurs principaux: Zhangyong Song, Yunlong Lin, Fang Du, Youping Yin, Zhongkang Wang
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis Group 2017-01-01
Collection:Mycology
Sujets:
Metarhizium rileyi
microsclerotia
submerged fermentation
central composite design
response surface methodology
aeration and agitation rate
Accès en ligne:http://dx.doi.org/10.1080/21501203.2017.1279688
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