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Core-shell hydrogel particles harvest, concentrate and preserve labile low abundance biomarkers.
The blood proteome is thought to represent a rich source of biomarkers for early stage disease detection. Nevertheless, three major challenges have hindered biomarker discovery: a) candidate biomarkers exist at extremely low concentrations in blood; b) high abundance resident proteins such as albumi...
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Hauptverfasser: | , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Public Library of Science (PLoS)
2009-01-01
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Schriftenreihe: | PLoS ONE |
Online Zugang: | http://europepmc.org/articles/PMC2651577?pdf=render |
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