Neuroprotective Effect of Ketone Metabolism on Inhibiting Inflammatory Response by Regulating Macrophage Polarization After Acute Cervical Spinal Cord Injury in Rats

ObjectiveTo investigate the effects of ketogenic metabolism on macrophage polarization, inflammation inhibition, and function recovery after acute spinal cord injury (SCI) in rats.MethodsSixty-four adult male Sprague–Dawley rats were randomly and equally divided into sham, standard diet (SD), ketone...

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Auteurs principaux: Junyu Lin, Zucheng Huang, Junhao Liu, Zhiping Huang, Yapu Liu, Qi Liu, Zhou Yang, Ruoyao Li, Xiuhua Wu, Zhe Shi, Qingan Zhu, Xiaoliang Wu
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020-10-01
Collection:Frontiers in Neuroscience
Sujets:
spinal cord injury
ketone metabolism
ketogenic diet
inflammation
macrophage
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fnins.2020.583611/full
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