Intravenous superoxide dismutase as a protective agent to prevent impairment of lung function induced by high tidal volume ventilation

Abstract Background Positive-pressure mechanical ventilation is essential in assisting patients with respiratory failure in the intensive care unit and facilitating oxygenation in the operating room. However, it was also recognized as a primary factor leading to hospital-acquired pulmonary dysfuncti...

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Bibliographic Details
Main Authors: Nan-Chun Wu, Fan-Ting Liao, Hao-min Cheng, Shih-Hsien Sung, Yu-Chun Yang, Jiun-Jr Wang
Format: Artigo
Language:Inglês
Published: BMC 2017-07-01
Series:BMC Pulmonary Medicine
Subjects:
Rats
Lung function
Superoxide dismutase
Inflammation
Oxidative stress
Nitric oxide
Online Access:http://link.springer.com/article/10.1186/s12890-017-0448-9
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