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Loss of KDM4B impairs osteogenic differentiation of OMSCs and promotes oral bone aging

Abstract Aging of craniofacial skeleton significantly impairs the repair and regeneration of trauma-induced bony defects, and complicates dental treatment outcomes. Age-related alveolar bone loss could be attributed to decreased progenitor pool through senescence, imbalance in bone metabolism and bo...

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Main Authors: Peng Deng, Insoon Chang, Jiongke Wang, Amr A. Badreldin, Xiyao Li, Bo Yu, Cun-Yu Wang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2022-05-01
Serija:International Journal of Oral Science
Online dostop:https://doi.org/10.1038/s41368-022-00175-3
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