Lymphopenia-induced proliferation of CD4 T-cells is associated with CD4 T-lymphocyte exhaustion in treated HIV-infected patients

Background & objectives: Under the lymphopenic condition, T-cells divide to maintain their peripheral pool size. Profound chronic lymphopenia in some treated HIV-infected patients, characterized by poor T-cell recovery, might result in intensive homeostatic proliferation and can cause T-cell exh...

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Autores principales: Evgeniya V Saidakova, Konstantin V Shmagel, Larisa B Korolevskaya, Nadezhda G Shmage, Valeriy A Chereshnev
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer Medknow Publications 2018-01-01
Colección:Indian Journal of Medical Research
Materias:
CD57 - exhaustion - HIV infection - lymphopenia - PD-1 - proliferation - T cell
Acceso en línea:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2018;volume=147;issue=4;spage=376;epage=383;aulast=Saidakova
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