Interplay of tRNA-Derived Fragments and T Cell Activation in Breast Cancer Patient Survival

Effector CD8<sup>+</sup> T cell activation and its cytotoxic function are positively correlated with improved survival in breast cancer. tRNA-derived fragments (tRFs) have recently been found to be involved in gene regulation in cancer progression. However, it is unclear how interactions...

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Autori principali: Nayang Shan, Ningshan Li, Qile Dai, Lin Hou, Xiting Yan, Amei Amei, Lingeng Lu, Zuoheng Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2020-08-01
Serie:Cancers
Soggetti:
breast cancer
T cell activation score
tRNA-derived fragments
pathway enrichment analysis
cancer survival
Accesso online:https://www.mdpi.com/2072-6694/12/8/2230
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