IL-21 receptor signaling is essential for control of hepatocellular carcinoma growth and immunological memory for tumor challenge

Hepatocellular carcinoma (HCC) is a typical inflammation-associated cancer. IL-21 regulates both innate and adaptive immune responses and has key roles in antitumor and antiviral responses. However, the role of IL-21 in HCC development is poorly defined. In the current study, we explored the role of...

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Hlavní autoři: Xinchun Zheng, Yang Zhou, Xuan Yi, Chengcong Chen, Chunhua Wen, Guofu Ye, Xiaoyi Li, Libo Tang, Xiaoyong Zhang, Fuqiang Yang, Guangze Liu, Yongyin Li, Jinlin Hou
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2018-12-01
Edice:OncoImmunology
Témata:
il-21 receptor
hcc
immune memory response
mouse hcc model
tumor-specific immune response
On-line přístup:http://dx.doi.org/10.1080/2162402X.2018.1500673
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