Chlamydophila pneumoniae induces expression of Toll-like Receptor 4 and release of TNF-α and MIP-2 via an NF-κB pathway in rat type II pneumocytes

<p>Abstract</p> <p>Background</p> <p>The role of alveolar type II cells in the regulation of innate and adaptive immunity is unclear. Toll-like receptors (TLRs) have been implicated in host defense. The purpose of the present study was to investigate whether Chlamydophi...

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Hlavní autoři: Maass Matthias, Richter Ekkehard, Koehne Petra, Schulz Christian, Wissel Heide, Rüdiger Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2005-06-01
Edice:Respiratory Research
Témata:
Chlamydophila (Chlamydia) pneumoniae
rat type II pneumocytes
TLR4
NF-κB
cytokines
On-line přístup:http://respiratory-research.com/content/6/1/51
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