Nephrotoxicity of immune checkpoint inhibitors beyond tubulointerstitial nephritis: single-center experience

Abstract Rationale & Objective The approved therapeutic indication for immune checkpoint inhibitors (CPIs) are rapidly expanding including treatment in the adjuvant setting, the immune related toxicities associated with CPI can limit the efficacy of these agents. The literature on the nephrotoxi...

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Hlavní autoři: Omar Mamlouk, Umut Selamet, Shana Machado, Maen Abdelrahim, William F. Glass, Amanda Tchakarov, Lillian Gaber, Amit Lahoti, Biruh Workeneh, Sheldon Chen, Jamie Lin, Noha Abdel-Wahab, Jean Tayar, Huifang Lu, Maria Suarez-Almazor, Nizar Tannir, Cassian Yee, Adi Diab, Ala Abudayyeh
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2019-01-01
Edice:Journal for ImmunoTherapy of Cancer
Témata:
Checkpoint inhibitors
Immunotherapy
Glomerulonephritis
Acute tubulointerstitial nephritis
On-line přístup:http://link.springer.com/article/10.1186/s40425-018-0478-8
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