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Recognition of TLR2 N-glycans: critical role in ArtinM immunomodulatory activity.
TLR2 plays a critical role in the protection against Paracoccidioides brasiliensis conferred by ArtinM administration. ArtinM, a D-mannose-binding lectin from Artocarpus heterophyllus, induces IL-12 production in macrophages and dendritic cells, which accounts for the T helper1 immunity that results...
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主要な著者: | , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Public Library of Science (PLoS)
2014-01-01
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シリーズ: | PLoS ONE |
オンライン・アクセス: | http://europepmc.org/articles/PMC4043963?pdf=render |
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