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Pharmacological Inhibition of PPAR<sub>y</sub> Boosts HIV Reactivation and Th17 Effector Functions, while Preventing Progeny Virion Release and <i>de novo</i> Infection
The frequency and functions of Th17-polarized CCR6+RORyt+CD4+ T cells are rapidly compromised upon HIV infection and are not restored with long-term viral suppressive antiretroviral therapy (ART). In line with this, Th17 cells represent selective HIV-1 infection targets mainly at mucosal sites, with...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Case Western Reserve University
2020-09-01
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| श्रृंखला: | Pathogens and Immunity |
| विषय: | |
| ऑनलाइन पहुंच: | https://paijournal.com/index.php/paijournal/article/view/348 |
| टैग : |
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