Pathways of topological rank analysis (PoTRA): a novel method to detect pathways involved in hepatocellular carcinoma

Complex diseases such as cancer are usually the result of a combination of environmental factors and one or several biological pathways consisting of sets of genes. Each biological pathway exerts its function by delivering signaling through the gene network. Theoretically, a pathway is supposed to h...

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Bibliographic Details
Main Authors: Chaoxing Li, Li Liu, Valentin Dinu
Format: Artigo
Language:Inglês
Published: PeerJ Inc. 2018-04-01
Series:PeerJ
Subjects:
PageRank
Biological pathways
PoTRA
Fisher’s exact test
Hepatocellular carcinoma
Kolmogorov–Smirnov test
Online Access:https://peerj.com/articles/4571.pdf
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