Modulation of Pleurodeles waltl DNA polymerase mu expression by extreme conditions encountered during spaceflight.

DNA polymerase µ is involved in DNA repair, V(D)J recombination and likely somatic hypermutation of immunoglobulin genes. Our previous studies demonstrated that spaceflight conditions affect immunoglobulin gene expression and somatic hypermutation frequency. Consequently, we questioned whether Polμ...

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Main Authors: Véronique Schenten, Nathan Guéguinou, Sarah Baatout, Jean-Pol Frippiat
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3729694?pdf=render
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