Evaluating screening approaches for hepatocellular carcinoma in a cohort of HCV related cirrhosis patients from the Veteran’s Affairs Health Care System

Abstract Background Hepatocellular carcinoma (HCC) has limited treatment options in patients with advanced stage disease and early detection of HCC through surveillance programs is a key component towards reducing mortality. The current practice guidelines recommend that high-risk cirrhosis patients...

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Главные авторы: Nabihah Tayob, Peter Richardson, Donna L. White, Xiaoying Yu, Jessica A. Davila, Fasiha Kanwal, Ziding Feng, Hashem B. El-Serag
Формат: Artigo
Язык:Inglês
Опубликовано: BMC 2018-01-01
Серии:BMC Medical Research Methodology
Предметы:
Early detection
Hepatocellular carcinoma
Longitudinal biomarkers
α-fetoprotein
Parametric empirical Bayes
Short-term risk prediction
Online-ссылка:http://link.springer.com/article/10.1186/s12874-017-0458-6
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