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Human phosphatidylethanolamine-binding protein 4 promoted the radioresistance of human rectal cancer by activating Akt in an ROS-dependent way.

Human phosphatidylethanolamine-binding protein 4(hPEBP4) is a novel anti-apoptosis molecule associated with the resistance of tumors to apoptotic agents. Here we sought to investigate the role of hPEBP4 in the radioresistance of rectal cancer. Immunohistochemistry analysis showed hPEBP4 was expresse...

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Библиографические подробности
Главные авторы: Jianming Qiu, Guangen Yang, Ali Lin, Zhong Shen, Dong Wang, Lei Ding
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2014-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3940727?pdf=render
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