TNF-α promotes extracellular vesicle release in mouse astrocytes through glutaminase

Abstract Background Extracellular vesicles (EVs) are membrane-contained vesicles shed from cells. EVs contain proteins, lipids, and nucleotides, all of which play important roles in intercellular communication. The release of EVs is known to increase during neuroinflammation. Glutaminase, a mitochon...

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Bibliographic Details
Main Authors: Kaizhe Wang, Ling Ye, Hongfang Lu, Huili Chen, Yanyan Zhang, Yunlong Huang, Jialin C. Zheng
Format: Artigo
Language:Inglês
Published: BMC 2017-04-01
Series:Journal of Neuroinflammation
Subjects:
TNF-α
Glutaminase
Extracellular vesicles
Astrocytes
Online Access:http://link.springer.com/article/10.1186/s12974-017-0853-2
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