Using High Resolution Melting method for detecting nucleotide polymorphisms of STK11 gene germline in patients with digestive system cancers

Abstract Background and Objective: High resolution melting (HRM) analysis is a technique to measure decrease of fluoresce, caused by discharge of the dye, throughout DNA thermal melting gradient process. STK11 gene encodes one of cellular serine-threonine kinase proteins that regulates cellular po...

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Autori principali: Seyed Jamal Hosseini, Ali Nazemi, Mehrdad Hashemi, Mirsaed Miri Nargesi, Sharashout Sharirfi, Abolfazl Movafagh, Farhad Shaveisi-Zadeh, Aliasghar karaminia
Natura: Artigo
Lingua:Inglês
Pubblicazione: West Asia Organization for Cancer Prevention 2017-11-01
Serie:Asian Pacific Journal of Cancer Biology
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Keywords: STK11 gene, mutation of germline, high resolution melting
Accesso online:http://www.waocp.org/journal/index.php/apjcb/article/view/12
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