Influence of ADAM10 Polymorphisms on Plasma Level of Soluble Receptor for Advanced Glycation End Products and The Association With Alzheimer’s Disease Risk

To determine the role of A disintegrin and metalloproteinase 10 (ADAM10) in genetic susceptibility to Alzheimer’s disease (AD) in a representative Chinese sample, we genotyped 362 AD patients and 370 healthy controls for the rs514049A/C and rs653765C/T polymorphisms in the ADAM10 promoter using the...

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Détails bibliographiques
Auteurs principaux: Wen-Hui Huang, Wei Chen, Lian-ying Jiang, Yi-Xia Yang, Li-Fen Yao, Ke-Shen Li
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018-11-01
Collection:Frontiers in Genetics
Sujets:
Alzheimer’s disease
ADAM10
single nucleotide polymorphism (SNP)
soluble receptor for advanced glycation end products
RAGE
Accès en ligne:https://www.frontiersin.org/article/10.3389/fgene.2018.00540/full
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