The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma

Interleukin-1 (IL-1) plays a key role in carcinogenesis and several IL-1-targeted therapeutics are under investigation for the treatment of pancreatic ductal adenocarcinoma (PDAC). We sought to broaden our understanding of how the family of IL-1 ligands and receptors impact the tumor immune landscap...

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Bibliographic Details
Main Authors: Kelly M. Herremans, Dominique D. Szymkiewicz, Andrea N. Riner, Riley P. Bohan, Gerik W. Tushoski, Aaron M. Davidson, XiangYang Lou, Man Chong Leong, Bayli DiVita Dean, Michael Gerber, Patrick W. Underwood, Song Han, Steven J. Hughes
Format: Artigo
Language:Inglês
Published: Elsevier 2022-06-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Pancreas cancer
Bioinformatics
Immunology
Immune checkpoint
Survival
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558622000185
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