The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma

Interleukin-1 (IL-1) plays a key role in carcinogenesis and several IL-1-targeted therapeutics are under investigation for the treatment of pancreatic ductal adenocarcinoma (PDAC). We sought to broaden our understanding of how the family of IL-1 ligands and receptors impact the tumor immune landscap...

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Bibliographische Detailangaben
Hauptverfasser: Kelly M. Herremans, Dominique D. Szymkiewicz, Andrea N. Riner, Riley P. Bohan, Gerik W. Tushoski, Aaron M. Davidson, XiangYang Lou, Man Chong Leong, Bayli DiVita Dean, Michael Gerber, Patrick W. Underwood, Song Han, Steven J. Hughes
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2022-06-01
Schriftenreihe:Neoplasia: An International Journal for Oncology Research
Schlagworte:
Pancreas cancer
Bioinformatics
Immunology
Immune checkpoint
Survival
Online Zugang:http://www.sciencedirect.com/science/article/pii/S1476558622000185
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