Unexpected complexity in the interference activity of a cloned influenza defective interfering RNA

Abstract Background Defective interfering (DI) viruses are natural antivirals made by nearly all viruses. They have a highly deleted genome (thus being non-infectious) and interfere with the replication of genetically related infectious viruses. We have produced the first potential therapeutic DI vi...

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Main Authors: Bo Meng, Kirsten Bentley, Anthony C. Marriott, Paul D. Scott, Nigel J. Dimmock, Andrew J. Easton
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-07-01
Serier:Virology Journal
Fag:
Influenza virus
Defective interfering RNA
Replication
Interference
Online adgang:http://link.springer.com/article/10.1186/s12985-017-0805-6
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