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Hyaluronan’s Role in Fibrosis: A Pathogenic Factor or a Passive Player?

Fibrosis is a debilitating condition that can lead to impairment of the affected organ’s function. Excessive deposition of extracellular matrix (ECM) molecules is characteristic of most fibrotic tissues. Fibroblasts activated by cytokines or growth factors differentiate into myofibroblasts that driv...

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Bibliographic Details
Main Authors: Sami Albeiroti, Artin Soroosh, Carol A. de la Motte
Format: Artigo
Language:Inglês
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/790203
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