Defining Essentiality Score of Protein-Coding Genes and Long Noncoding RNAs

Measuring the essentiality of genes is critically important in biology and medicine. Here we proposed a computational method, GIC (Gene Importance Calculator), which can efficiently predict the essentiality of both protein-coding genes and long noncoding RNAs (lncRNAs) based on only sequence informa...

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Hauptverfasser: Pan Zeng, Ji Chen, Yuhong Meng, Yuan Zhou, Jichun Yang, Qinghua Cui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018-10-01
Schriftenreihe:Frontiers in Genetics
Schlagworte:
essentiality
protein-coding genes
lncRNAs
prediction
machine learning
Online Zugang:https://www.frontiersin.org/article/10.3389/fgene.2018.00380/full
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