ICAM-1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria model

Abstract Background Parasite cytoadherence within the microvasculature of tissues and organs of infected individuals is implicated in the pathogenesis of several malaria syndromes. Multiple host receptors may mediate sequestration. The identity of the host receptor(s), or the parasite ligand(s) resp...

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Autori principali: Deirdre A. Cunningham, Jing-wen Lin, Thibaut Brugat, William Jarra, Irene Tumwine, Garikai Kushinga, Jai Ramesar, Blandine Franke-Fayard, Jean Langhorne
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2017-05-01
Serie:Malaria Journal
Soggetti:
Plasmodium chabaudi
Sequestration
ICAM-1
CD36
Schizont membrane-associated cytoadherence protein
SMAC
Accesso online:http://link.springer.com/article/10.1186/s12936-017-1834-8
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