Evaluation of the Performance of AmpliSeq and SureSelect Exome Sequencing Libraries for Ion Proton

Library preparation for whole-exome sequencing is a critical step serving the enrichment of the regions of interest. For Ion Proton, there are only two exome library preparation methods available, AmpliSeq and SureSelect. Although of major interest, a comparison of the two methods is hitherto missin...

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Hauptverfasser: Piyush Gampawar, Yasaman Saba, Ulrike Werner, Reinhold Schmidt, Bertram Müller-Myhsok, Helena Schmidt
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019-09-01
Schriftenreihe:Frontiers in Genetics
Schlagworte:
exome sequencing
ion proton sequencer
AmpliSeq
SureSelect
library preparation
validation
Online Zugang:https://www.frontiersin.org/article/10.3389/fgene.2019.00856/full
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