Evaluation of the Performance of AmpliSeq and SureSelect Exome Sequencing Libraries for Ion Proton

Library preparation for whole-exome sequencing is a critical step serving the enrichment of the regions of interest. For Ion Proton, there are only two exome library preparation methods available, AmpliSeq and SureSelect. Although of major interest, a comparison of the two methods is hitherto missin...

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Bibliografiska uppgifter
Huvudupphovsmän: Piyush Gampawar, Yasaman Saba, Ulrike Werner, Reinhold Schmidt, Bertram Müller-Myhsok, Helena Schmidt
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019-09-01
Serie:Frontiers in Genetics
Ämnen:
exome sequencing
ion proton sequencer
AmpliSeq
SureSelect
library preparation
validation
Länkar:https://www.frontiersin.org/article/10.3389/fgene.2019.00856/full
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