lncRNA TUG1 modulates proliferation, apoptosis, invasion, and angiogenesis via targeting miR-29b in trophoblast cells

Abstract Background Pre-eclampsia (PE) is regarded as the leading cause of maternal and neonatal morbidity and mortality. Nevertheless, the potential mechanism for the regulation of trophoblast behaviors and the pathogenesis of PE remain largely elusive. Recently, accumulating evidence emphasized th...

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Main Authors: Qian Li, Jing Zhang, Dong-Mei Su, Li-Na Guan, Wei-Hong Mu, Mei Yu, Xu Ma, Rong-Juan Yang
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2019-09-01
Series:Human Genomics
Assuntos:
Pre-eclampsia
lncRNA TUG1
miR-29b
MCL1
VEGFA
MMP2
Acceso en liña:http://link.springer.com/article/10.1186/s40246-019-0237-z
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