Clinical significance of tumor necrosis factor-α-863 C/A and -1031 T/C promoter polymorphisms in systemic lupus erythematosus patients: Relation to disease activity and damage

Aim of the work: To assess the clinical significance of serum levels of tumor necrosis factor alpha (TNF-α) and its -863 C/A and 1031 T/C promoter polymorphism in systemic lupus erythematosus (SLE) patients and find any association to disease activity and damage. Patients and methods: Forty-two fema...

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Main Authors: Al-Hussein M. El-Dakrony, Iman El-Gazzar, Safaa Sayed, Wael Sadek, Hussein El-Fishawy, Olfat Shaker
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2017-10-01
Sraith:Egyptian Rheumatologist
Ábhair:
TNF-α
-863C/A, -1031T/C
Promoter polymorphism
Systemic lupus erythematosus
SLEDAI
Rochtain Ar Líne:http://www.sciencedirect.com/science/article/pii/S1110116417300509
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