A novel and sensitive DNA methylation marker for the urine-based liquid biopsies to detect bladder cancer

Abstract Background Better prognostic outcome is closely correlated with early detection of bladder cancer. Current non-invasive urianalysis relies on simultaneously testing multiple methylation markers to achieve relatively high accuracy. Therefore, we have developed an easy-to-use, convenient, and...

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Hauptverfasser: Leihong Deng, Haichao Chao, Huanhuan Deng, Zhaojun Yu, Rongsong Zhao, Longwu Huang, Yun Gong, Yueting Zhu, Qingping Wang, Feng Li, Lirong Liu, Lei He, Zhimin Tang, Caizhi Liao, Yan Qi, Xianshu Wang, Tao Zeng, Hongzhi Zou
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-05-01
Schriftenreihe:BMC Cancer
Schlagworte:
Bladder cancer (BC)
Urine-based DNA (uDNA) test
Methylation biomarker
Sensitivity
Specificity
Online Zugang:https://doi.org/10.1186/s12885-022-09616-y
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