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Induction of thyroid gene expression and radioiodine uptake in melanoma cells: novel therapeutic implications.
Both the MAP kinase and PI3K/Akt pathways play an important role in the pathogenesis of melanoma. We conducted the present study to test the hypothesis that targeting the two pathways to potently induce cell inhibition accompanied with thyroid iodide-handling gene expression for adjunct radioiodine...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2009-07-01
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| Edice: | PLoS ONE |
| On-line přístup: | http://europepmc.org/articles/PMC2703805?pdf=render |
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