DNA methylation-based measures of accelerated biological ageing and the risk of dementia in the oldest-old: a study of the Lothian Birth Cohort 1921

Abstract Background Previous studies have demonstrated an association between DNA methylation-based measures of accelerated ageing and age-related health outcomes and mortality. As a disease closely associated with advancing age, we hypothesized that DNA methylation-based measures of accelerated age...

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Main Authors: Ruth A. Sibbett, Drew M. Altschul, Riccardo E. Marioni, Ian J. Deary, John M. Starr, Tom C. Russ
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-02-01
Serier:BMC Psychiatry
Fag:
Dementia
DNA methylation
Accelerated ageing
Epigenetic age
Online adgang:http://link.springer.com/article/10.1186/s12888-020-2469-9
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